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Exercise regularly—at least 150 minutes per week—to maintain a healthy weight and avoid liver fat accumulation.

“This nutrient helps package and ship fat out of the liver,” she says, which could otherwise eventually lead to nonalcoholic fatty liver disease. “Keeping your choline levels up is a small move that makes a big difference in keeping your liver running clean and clear,” she says.

Systematic reviews have found that cannabinoids may be modestly effective for some chronic pain, primarily neuropathic pain, based on limited evidence,43,44 However, the evidence is largely based on studies of high THC-containing products, which also show high rates of adverse events, such as sedation and psychomotor impairment.

Watch for side effects. If you feel sleepy or dizzy during the day or if you experience any other side effects that bother you, talk to your health care provider.

Anticonvulsants are useful adjuncts in the management of neuropathic pain. They typically will not be helpful for acute pain, rather are more commonly used for chronic neuropathic pain.

When treatment goals have been met or when progress plateaus, formal therapy may be discontinued, but advise patients to continue with a program of independent daily home exercise.

"Retinoids can also increase sun sensitivity, so they are best applied at night. An SPF moisturizer should be applied in the morning."

A logical rationale for an intervention does not ensure the patient’s acceptance and participation in it. A patient’s acceptance of therapy is influenced by several complex factors, including characteristics of illness and identity.

Pregabalin is a federal Schedule V controlled substance, and gabapentin has been scheduled in many states. Both of these medications produce an increased addiction risk.

Consider methadone for its prolonged duration of effect, which is useful for longer term therapy and minimizes euphoria with low doses.

All patients being discharged with opioid medications should receive counseling on the use of prescription opioids.

Consider prescribing systemic or topical non-opioid medications as an adjunct to the non-pharmacologic treatments noted above. Medications often have limited effectiveness, significant interactions or toxicity, and may promote false beliefs about the benefit get more info of medications.

Substance use disorder complicating the treatment of chronic pain. The prevalence of substance use disorder among patients with chronic pain is significant. Studies have repeatedly demonstrated that at least 20% of opioid-treated patients misuse or divert their medication.

If PRN medication is required ≥ 3×/day → inadequate analgesia likely; review the regular medication Additionally, concurrent treatment with adjuvant drugs

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